Fmoc Soild Phase Peptide Synthesis: A Practical Approach (Practical Approach Series (Paperback))

Book Description

In the years since the publication of Atherton and Sheppard's volume, the technique of Fmoc solid-phase peptide synthesis has matured considerably and is now the standard approach for the routine production of peptides. The basic problems at the time of publication of this earlier work have now for the most part, been solved. As a result, innovators in the field have focussed their efforts to develop methodologies and chemistry for the synthesis of more complex structures. The focus of this new volume is much broader, and covers the essential procedures for the production of linear peptides and more advanced techniques for preparing cyclic, side-chain modified, phospho- and glycopeptides. Many other methods also deserving attention have been included: convergent peptide synthesis; peptide-protein conjugation; chemoselective ligation; and chemoselective purification. The difficult preparation of cysteine and methionine-containing peptides is also covered, as well as methods for overcoming aggregation during peptide chain assembly. Many of the techniques developed for the production of large arrays of peptides by parallel synthesis, such as t-bag, SPOT and PIN synthesis, have naturally been included. Finally, a survey of available automated instrumentation has also been provided.

Customer Reviews:

Good book for peptide chemist........2004-11-04

This is a good book for peptide chemist. It has detailed protocol for almost all useful information about Fmoc solid phase peptide synthesis which is used in most of the peptide company, in our company, this book acts as a standard reference for our daily production. I strongly recommend you to buy one if you are or you want to be a peptide chemist.

Methods in Enzymology, Volume 289: Solid-Phase Peptide Synthesis (Methods in Enzymology)

Average customer rating:

Methods in Enzymology, Volume 289: Solid-Phase Peptide Synthesis (Methods in Enzymology)
GREGG B. FIELDS
Manufacturer: Academic Press
ProductGroup: Book
Binding: Hardcover

Biochemistry | Biological Sciences | Science | Subjects | Books

General | Science | Subjects | Books

Biochemistry | Basic Science | Medicine | Subjects | Books

General | Medicine | Subjects | Books

Biochemistry | Medicine | New & Used Textbooks | Stores | Books

Nursing | Medicine | New & Used Textbooks | Stores | Books

All Amazon Upgrade | Amazon Upgrade | Stores | Books

Engineering | Amazon Upgrade | Stores | Books

Medicine | Amazon Upgrade | Stores | Books

Professional & Technical | Amazon Upgrade | Stores | Books

Science | Amazon Upgrade | Stores | Books

All Titles | Qualifying Textbooks - Fall 2007 | Stores | Books
ASIN: 0121821900

Book Description

The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volumehas been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. More than 275 volumes have been published (all of them still in print) and much of the material is relevant even today-truly an essential publication for researchers in all fields of life sciences.

Key Features
* Solid-phase peptide synthesis
* Applications of peptides for structural and biological studies
* Characterization of synthetic peptides

Solid Support Oligosaccharide Synthesis and Combinatorial Carbohydrate Libraries

Average customer rating:

Solid Support Oligosaccharide Synthesis and Combinatorial Carbohydrate Libraries
Peter H. Seeberger
Manufacturer: John Wiley & Sons
ProductGroup: Book
Binding: Hardcover

Biochemistry | Biological Sciences | Science | Subjects | Books

General & Reference | Chemistry | Science | Subjects | Books

General | Science | Subjects | Books

Pharmacy | Pharmacology | Medicine | Subjects | Books

Biochemistry | Medicine | New & Used Textbooks | Stores | Books

Book Description

Solid-phase synthesis of carbohydrates presents unique challenges to synthetic chemists and currently represents one of the hottest areas of research in bioorganic chemistry. Solid Support Oligosaccharide Synthesis and Combinatorial Carbohydrate Libraries addresses the exciting expectation that solid-phase assembly of oligosaccharides will have a fundamental impact on the field of glycobiology. This publication details the methodologies currently investigated for the attachment of carbohydrates to beads, synthesis including coupling strategies, and removal of the product from beads.
With chapters written by eminent contributing authors, the material explores different synthetic strategies, glycosylation protocols, the use of solid supports versus soluble polymeric supports, and "on-resin" analytical methods. Tremendous progress in the field has set the stage for Solid Support Oligosaccharide Synthesis and Combinatorial Carbohydrate Libraries to provide a wealth of information on such topics as:

Specific oligosaccharide structures used in signal transduction processes
Preparation and screening of glycopeptide libraries
Solid-phase carbohydrate synthesis

Download Description

Specific oligosaccharide structures used in signal transduction processes
Preparation and screening of glycopeptide libraries
Solid-phase carbohydrate synthesis

Bruce Merrifield: Life During a Golden Age of Peptide Chemistry: The Concept and Development of Solid-Phase Peptide Synthesis (Profiles, Pathways, and Dreams)

Average customer rating:

Bruce Merrifield: Life During a Golden Age of Peptide Chemistry: The Concept and Development of Solid-Phase Peptide Synthesis (Profiles, Pathways, and Dreams)
Bruce Merrifield
Manufacturer: An American Chemical Society Publication
ProductGroup: Book
Binding: Hardcover

General | Biographies & Memoirs | Subjects | Books

Scientists | Professionals & Academics | Biographies & Memoirs | Subjects | Books

Biochemistry | Biological Sciences | Science | Subjects | Books

General & Reference | Chemistry | Science | Subjects | Books

General | Science | Subjects | Books

General | History & Philosophy | Science | Subjects | Books

History of Technology | Technology | Science | Subjects | Books

Biochemistry | Basic Science | Medicine | Subjects | Books

All Titles | Qualifying Textbooks - Fall 2007 | Stores | Books
ASIN: 0841218420

Book Description

Bruce Merrifield, eminent American scientist, 1984 Nobel Prize winner and professor at The Rockefeller University, is noted for his single-handed development of solid phase peptide synthesis. The progress of biochemistry and related fields is closely correlated with the availability of pure peptides, and in this volume, Merrifield describes nearly 40 years of progress. The warmth and kindness of this sincere gentleman is described by his personal experiences. Many photographs depict both the professional as well as the personal side of Bruce Merrifield.

Immobilized Catalysts: Solid Phases, Immobilization and Applications (Topics in Current Chemistry)

Average customer rating:

Immobilized Catalysts: Solid Phases, Immobilization and Applications (Topics in Current Chemistry)
Andreas, Ed. Kirschning
Manufacturer: Springer-Verlag, Inc.
ProductGroup: Book
Binding: Hardcover

Biochemistry | Biological Sciences | Science | Subjects | Books

General & Reference | Chemistry | Science | Subjects | Books

General | Science | Subjects | Books

All Amazon Upgrade | Amazon Upgrade | Stores | Books

Engineering | Amazon Upgrade | Stores | Books

Medicine | Amazon Upgrade | Stores | Books

Professional & Technical | Amazon Upgrade | Stores | Books

Science | Amazon Upgrade | Stores | Books

All Titles | Qualifying Textbooks - Fall 2007 | Stores | Books

Medicine | Qualifying Textbooks - Fall 2007 | Stores | Books

Professional | Qualifying Textbooks - Fall 2007 | Stores | Books

Science | Qualifying Textbooks - Fall 2007 | Stores | Books
ASIN: 3540209158

Immunochemistry Of Solid-phase Immunoassay

Average customer rating:

Immunochemistry Of Solid-phase Immunoassay
JOHN, ED. BUTLER
Manufacturer: CRC
ProductGroup: Book
Binding: Hardcover

Biochemistry | Biological Sciences | Science | Subjects | Books

Research | Education | Science | Subjects | Books

Methodology & Statistics | Experiments, Instruments & Measurement | Science | Subjects | Books

General | Science | Subjects | Books

Immunology | Basic Science | Medicine | Subjects | Books

Microbiology | Basic Science | Medicine | Subjects | Books

General | Medicine | Subjects | Books

All Titles | Qualifying Textbooks - Fall 2007 | Stores | Books
ASIN: 0849353947

Book Description

Immunochemistry of Solid-Phase Immunoassay fills a nichÃ© in the field of immunoassay and immunology. Although solid-phase immunoassay constitutes a major technology in biology and medicine, there is no comprehensive source devoted to the immunochemical principles involved. As a result, this book will benefit students, technicians, and researchers who use this technology, as well as immunodiagnostic and biotech companies who develop the technology. The book is not a methods manual; instead, it incorporates the concepts, data, and opinions of more than 25 investigators working in this field. Topics discussed include: the chemistry of solid-phases, the behavior or antibodies and antigens on solid phases, membrane solid-phases, reaction kinetics, antigen quantitation, enzyme systems, photophysics, immunochemical considerations in data analyses, multianalyte assays and occupancy concepts, antibody quantitation, streptavidin, a review of data analysis software, and solid-phase peptide immunoassay.

Solid Phase Biochemistry (Chemical Analysis)

Average customer rating:

Solid Phase Biochemistry (Chemical Analysis)
William H. Scouten
Manufacturer: John Wiley & Sons Inc
ProductGroup: Book
Binding: Hardcover

Biochemistry | Biological Sciences | Science | Subjects | Books

Physiology | Basic Science | Medicine | Subjects | Books

Average customer rating:

Solid-Phase Organic Syntheses, Volume 1
Anthony W. Czarnik
Manufacturer: John Wiley & Sons
ProductGroup: Book
Binding: Hardcover

Biochemistry | Biological Sciences | Science | Subjects | Books

General & Reference | Chemistry | Science | Subjects | Books

General | Science | Subjects | Books

General | Medicine | Subjects | Books

Book Description

The rapid expansion of combinatorial chemistry has renewed interest in solid-phase organic synthesis, a method that lends itself well to creating and screening large numbers of lead compounds. Solid-Phase Organic Syntheses, Volume 1 is the first volume in a series that will be updated annually, filling a gap in the existing chemical literature. Providing information previously unavailable from a single resource, this series is dedicated to providing researchers in the field with validated and tested methods for the solid-phase synthesis of interesting and biologically relevant molecules.
Solid-phase methods will virtually always be invented for application in combinatorial organic synthesis. To meet these specific needs, Solid-Phase Organic Syntheses, Volume 1 focuses on a single type of synthetic transformation accomplished on solid support, and indicates how procedures are optimized to work with a structurally-wide variety of reagents. Written by recognized leaders in the field who review and test all chemical protocols before publication, organic transformations are organized by type of compound synthesized and reaction type.
For the first time, experimental details for proven solid-phase synthetic molecules are collected in a single, invaluable resource. Solid-Phase Organic Syntheses, Volume 1 provides combinatorial chemists and researchers in organic chemistry and medicinal chemistry with the tools and descriptive protocols to achieve syntheses of desired compounds using a variety of solid supports and reagents.

Solid-Phase Synthesis: A Practical Guide

Average customer rating:

Solid-Phase Synthesis: A Practical Guide
Steven A., Ed. Kates
Manufacturer: CRC
ProductGroup: Book
Binding: Hardcover

Biochemistry | Biological Sciences | Science | Subjects | Books

General & Reference | Chemistry | Science | Subjects | Books

General | Science | Subjects | Books

General | Engineering | Professional & Technical | Subjects | Books

Book Description

This volume provides the information needed to synthesize peptides by solid-phase synthesis (SPS) - employing polymeric support (resins), anchoring linkages (handles), coupling reagents (activators), and protection schemes. It presents strategies for creating a wide variety of compounds for drug discovery and analyzes peptides, DNA, carbohydrates, conjugates of biomolecules, and small molecules.

Solidification: Real-Time Investigation of Grain Nucleation and Growth During Liquid to Solid Phase Transformation of Aluminum Alloys

Average customer rating:

Solidification: Real-Time Investigation of Grain Nucleation and Growth During Liquid to Solid Phase Transformation of Aluminum Alloys
N. Iqbal
Manufacturer: IOS Press/Delft University Press
ProductGroup: Book
Binding: Paperback

Biochemistry | Biological Sciences | Science | Subjects | Books

General | Science | Subjects | Books

All Titles | Qualifying Textbooks - Fall 2007 | Stores | Books
ASIN: 9040725896

Product Description

In pure aluminum the nucleation of a new solid phase during the liquid-to¬solid phase transformation is activated by a relatively large undercooling of the melt with respect to the transformation temperature...

Book Description

From dining in the "gourmet ghetto" of Palermo and dancing in San Telmo's best tango bars to wandering in the legendary Pampas, land of the gaucho, Moon Handbooks Buenos Aires is the guide to the best the city has to offer, both on and off the beaten path. Practical information includes suggested travel strategies and lists of must-see sights, plus essentials on dining, transportation, and accommodations for a range of budgets. Complete with details for exploring Montevideo's new Ruta del Vino (wine route), lounging on Uruguay's glamorous beaches, and taking in Argentina's burgeoning art scene, Moon Handbooks Buenos Aires gives travelers the tools they need to create a more personal and memorable experience.

Customer Reviews:

Best yet.......2006-11-07

I have traveled to most all "corners" of the world and purchased many guidebooks. This one is without a doubt the best yet. The prices quoted are about 2/3 of actual but the economy in Argentina changes quickly at times and all are in relation to inflated costs per vendor. My congratulations to the writer and thank you for making my trip so much better!

This guide is in desperate need of an update. Not Recommended. .......2006-04-09

Of the five Argentina guides I brought with me (3/2006) this guide is the least useful and, the most out of date. Do not let the publishing date fool you; the information in this guide comes from research done in 2001/2002.

In the past four years much has changed in Buenos Aires. None of the hotel rates given in this guide are anywhere near what is being charged today. There are hotels that charge triple what this guide quotes.

The writing is uninspired and reads like something that you would read a government office of tourism. There is little information to helps you connect with the unique culture and characteristics of Buenos Aires. The maps in this guide are very difficult to use. The publisher has crammed everything on one map: hotels, restaurants, sights to see, etc. There are much better maps in other guides. The guide's recommendations for restaurants is sub-par in comparison to other guides.

For Buenos Aires, one of the best guides out is Fodor's `Argentina'. Fodor's has excellent maps of the city and it has great recommendations for both restaurants and accommodations. Caveat: only use Fodor's `Argentina' (3rd edition) for Buenos Aires, outside of the capitol Fodor's is dismal as a guide. For a great all around Argentina guide consider either Lonely Planet Argentina 2005 or Rough Guide Argentina 2005. This guide is not recommended.

Good writing, excellent layout.......2006-01-17

I just spent six weeks in Buenos Aires and used this book as a guide to my daily activities. Useful for more than just getting around, the book gives a careful, balanced view of many aspects of life in BsAs. The list of suggested readings in the back of the book shows the author's good taste. Instead of a book filled with hyperboles and hasty suggestions, you have a volume of reliable, thoughtful observations. An excellent companion to the beautiful city.

The best of a small bunch.......2003-12-21

South American guidebooks aren't as plentiful as those from other parts of the world, so I often have to buy several to get complete information. This Buenos Aires edition from Moon Handbooks was surprising because it not only included some great information on the city, but had better information on surrounding areas like Montevideo than my other Uruguay book. Also included up-to-date hotel information that was simply missing from the others.

Books:

Books Index

Books Home

Recommended Books