What's Wrong with My Mouse?: Behavioral Phenotyping of Transgenic and Knockout Mice

Book Description

Transgenic and knockout mutations provide an important means for understanding gene function, as well as for developing therapies for genetic diseases. This engaging and informative book discusses the many advances in the field of transgenic technology that have enabled researchers to bring about various changes in the mouse genome. Equal emphasis is given to both the principles of transgenic and knockout methods and their applications. A clear and concise format provides researchers with a comprehensive review of the behavioral paradigms appropriate for analyzing mouse phenotypes.

What's Wrong with My Mouse? explains the differences between transgenic knockout mice and their wild-type controls, while providing critical information about gene function and expression. This volume recognizes that newly identified genes can provide useful insights into brain functioning, including brain malfunctioning in disease states. Written by a world-renowned expert in the field, the material also covers:
* How to generate a transgenic or knockout mouse
* functions (open field, holeboard, rotarod, balance, grip, circadian activity, etc.)
* Sensory abilities (olfaction, vision, hearing, taste, touch, nociception)
* Reproductive behavior, social behavior, and emotional behavior

Researchers in neuroscience, pharmacology, genetics, developmental biology, and cell biology will all find this book essential reading.

Customer Reviews:

Valuable Book.......2002-11-19

"...this valuable book is currently the most complete overview of behavioral procedures available...it is a must have and a must read book..." (Genes, Brain, and Behavior, 2002)

Essential Book.......2001-07-24

"I would recommend that every behavioral scientist has at least two copies, one for their own use and one that will be on permanent loan to their students, post-doctoral students and colleagues in molecular biology." -- TRENDS in Pharmacological Sciences (Gerard R. Dawson, Merck Sharp & Dohme Research Laboratories)

Expert Review.......2001-07-24

"[T]his volume succeeds as a useful introduction to the realm of behavioral phenotyping for those interested in creating or using the large and increasing number of promising targeted mutant mice." -- TRENDS in Neurosciences (John K. Belknap, Oregon Health Sciences University)

Review.......2000-06-15

It is a much prized addition... and fulfills a heretofore unmet need for a comprehensive sourcebook of mutant mouse literature and procedures. In addition to its reference utility, Dr. Crawley's text can exert a valuable influence on the future of transgenic and knockout mouse research by standardizing behavioral phenotyping methods according to the present state-of-the-art. --Stephen C. Heinrichs, Ph.D., Boston College

an excellent resource.......2000-06-08

Very timely given the increasingly recognized importance of providing behavioral phenotypes of mutant mice. I would recommend the book with enthusiasm. --Eric Nestler, Yale University School of Medicine

The Behavior of the Laboratory Rat: A Handbook with Tests

Average customer rating:

The Behavior of the Laboratory Rat: A Handbook with Tests

Manufacturer: Oxford University Press, USA
ProductGroup: Book
Binding: Hardcover

General | Medicine | Subjects | Books

All Titles | Qualifying Textbooks - Fall 2007 | Stores | Books

Medicine | Qualifying Textbooks - Fall 2007 | Stores | Books

Professional | Qualifying Textbooks - Fall 2007 | Stores | Books

Science | Qualifying Textbooks - Fall 2007 | Stores | Books
Similar Items:

ASIN: 0195162854

Book Description

More is known about the behavior, anatomy, and molecular biology of the laboratory rat than any other animal species. Although its natural history and psychological functions have been described previously in books, this is the first comprehensive description of its behavior. Both seasoned and beginning investigators will be amazed at the range and complexity of the species as described in the 43 chapters of this volume. The behavioral descriptions are closely tied to the laboratory methods from which they were derived, thus allowing investigators to correlate the behavior and methods and exploit them in their own research. This book is aimed at investigators in neuroscience who may not be familiar with rat behavior, but who wish to incorporate behavioral studies into their own research. Nevertheless, seasoned investigators will also find the book to be a handy reference for behavioral paradigms with which they may not be familiar. It is expected that as the genetic and molecular understanding of the rat develops, there will be an increasing need for knowledge about rat behavior. This book will serve as an indispensable resource for neuroscientists, psychologists, pharmacologists, geneticists, molecular biologists, zoologists, and their students and trainees.

Mouse Genetics and Transgenics: A Practical Approach

Average customer rating:

Mouse Genetics and Transgenics: A Practical Approach

Manufacturer: Oxford University Press, USA
ProductGroup: Book
Binding: Paperback

Genetics | Evolution | Science | Subjects | Books

Chaos & Systems | Physics | Science | Subjects | Books

Experiments & Projects | Experiments, Instruments & Measurement | Science | Subjects | Books

General | Science | Subjects | Books

Genetics | Basic Science | Medicine | Subjects | Books

General | Parenting & Families | Subjects | Books

All Titles | Qualifying Textbooks - Fall 2007 | Stores | Books

Medicine | Qualifying Textbooks - Fall 2007 | Stores | Books

Parenting & Families | Qualifying Textbooks - Fall 2007 | Stores | Books

Professional | Qualifying Textbooks - Fall 2007 | Stores | Books

Science | Qualifying Textbooks - Fall 2007 | Stores | Books
Similar Items:

Accessories:

ASIN: 0199637083

Book Description

A unique book that integrates knowledge from a wide range of expertise, specifically applied to the mouse, and addressed at a wide audience from those new to the field to experts who want an update on the state of the art. Mouse Genetics and Transgenics: APA covers all aspects of using the mouse as a genetic model organism: care and husbandry; archiving stocks as frozen embryos or sperm; making new mutations by chemical mutagenesis; transgenesis; and gene targetting; mapping mutations and polygenic traits by cytogenetic, genetic, and physical means; and disseminating and researching information via the Internet.

Exploring Animal Behavior in Laboratory and Field: An Hypothesis-testing Approach to the Development, Causation, Function, and Evolution of Animal Behavior

Average customer rating:

Excellent resource for those teaching behavior labs
An assemblage of studious, college-level essays

Exploring Animal Behavior in Laboratory and Field: An Hypothesis-testing Approach to the Development, Causation, Function, and Evolution of Animal Behavior
Bonnie J. Ploger , and Ken Yasukawa
Manufacturer: Academic Press
ProductGroup: Book
Binding: Paperback

Social Psychology & Interactions | Psychology & Counseling | Health, Mind & Body | Subjects | Books

General | Science | Subjects | Books

General | Behavioral Sciences | Science | Subjects | Books

General | Veterinary Medicine | Medicine | Subjects | Books

All Amazon Upgrade | Amazon Upgrade | Stores | Books

Health, Mind & Body | Amazon Upgrade | Stores | Books

Medicine | Amazon Upgrade | Stores | Books

Professional & Technical | Amazon Upgrade | Stores | Books

Science | Amazon Upgrade | Stores | Books

All Titles | Qualifying Textbooks - Fall 2007 | Stores | Books
Similar Items:

ASIN: 0125583303

Book Description

Exploring Animal Behavior in Laboratory and Field is designed to provide a variety of exercises that engage students actively in all phases of scientific investigation, from formulating research questions through interpreting and presenting final results. It attempts to share the collective teaching expertise and experience of members of the Animal Behavior Society with all who are willing to benefit from their wisdom. Four types of exercises are presented: (1) traditional exercises in which students follow a pre-determined protocol to test particular hypotheses explicitly stated in the exercise, (2) traditional exercises that can easily be adapted to inquiry-based approaches, (3) combined pedagogy exercises that involve both traditional and inquiry approaches, and (4) inquiry exercises in which students first brainstorm to generate their own hypotheses, then design their own experiements to test their hypotheses.

* Supports a range of pedagogical styles and texts in animal behavior with active learning experiences that engage students
* Students and instructors benefit from knowledge and experience of members of the Animal Behavior Society
* Flexibility of design enables students and instrucotrs to tailor the exercises to their needs
* Can be used to support lab courses that are completely inquiry based as well as independent student research projects in animal behavior
* Consideration of animal care guidelines provides an excellent way to address and discuss concerns about the use of animals in teaching and research
* Emphasizes the hypothetico-deductive approach that students have difficulty understanding and implementing
* Supporting materials make additional required texts unnecessary and link study design considerations with real studies

Customer Reviews:

Excellent resource for those teaching behavior labs.......2003-07-09

This is a fantastic and much-needed book. As a resource for someone setting up a laboratory course in animal behavior, this book is full of excellent ideas, and I would advise anyone to get a copy of this book. The problem with adopting it as a lab book for students is that there are over 30 labs presented here. As many are multiweek projects, the most that could reasonably be done in a semester is 7-10 labs. Anyone who has taught students knows that having them purchase a book ... for which they will only use 1/4 or 1/3 of the chapters is only inviting a tremendous amount of griping. This is my only complaint with this book, which the publisher was pushing as a lab manual for students, instead of a resource for instructors.

An assemblage of studious, college-level essays.......2002-12-08

Collaboratively assembled and edited by Bonnie J. Ploger (Hamline University) and Ken Yasukawa (Beloit College), Exploring Animal Behavior In Laboratory And Field is a scholarly compendium offering a variety of diverse approaches to the development, function, and evolution of animal behavior, with contribution each being grounded in the creation and careful testing of scientific hypotheses. An assemblage of studious, college-level essays on select topics ranging from the response of tree squirrels to different types of alarm calls, to human nonverbal communications, to chemoreception in lizards, and a great deal more, Exploring Animal Behavior In Laboratory And Field would make an especially welcome addition to Zoological Studies reference collections and Wildlife Studies reading lists.

Naturalistic Environments in Captivity for Animal Behavior Research (Suny Series in Endangered Species)

Average customer rating:

Naturalistic Environments in Captivity for Animal Behavior Research (Suny Series in Endangered Species)
Edward F. Gibbons , and Everett J. Wyers
Manufacturer: State University of New York Press
ProductGroup: Book
Binding: Hardcover

General | Veterinary Medicine | Medicine | Subjects | Books

Reference | Outdoors & Nature | Subjects | Books

Animal Husbandry | Agricultural Sciences | Science | Subjects | Books

Average customer rating:

Animal Behavior in Laboratory and Field
Allen W. -editor Stokes
Manufacturer: W. H. Freeman & Company
ProductGroup: Book
Binding: Hardcover
ASIN: B000MGXLVW

Average customer rating:

Animal Behavior in Laboratory and Field
Allen W. Stokes
Manufacturer: W. H. freeman and Co
ProductGroup: Book
Binding: Paperback
ASIN: B000JVENLM

Average customer rating:

Animal Behavior in the Laboratory
Paul Silverman
Manufacturer: Universe Books
ProductGroup: Book
Binding: Hardcover

General | Animal Care & Pets | Home & Garden | Subjects | Books

Animal behavior: Teacher's supplement (Laboratory blocks for biology)

Average customer rating:

Animal behavior: Teacher's supplement (Laboratory blocks for biology)
Harper Follansbee
Manufacturer: Heath
ProductGroup: Book
Binding: Unknown Binding
ASIN: B0007EO36G

Animal Cognition in Nature: The Convergence of Psychology and Biology in Laboratory and Field

Average customer rating:

Animal Cognition in Nature: The Convergence of Psychology and Biology in Laboratory and Field

Manufacturer: Academic Press
ProductGroup: Book
Binding: Hardcover

General | Mental Health | Health, Mind & Body | Subjects | Books

Social Psychology & Interactions | Psychology & Counseling | Health, Mind & Body | Subjects | Books

General | Evolution | Science | Subjects | Books

General | Science | Subjects | Books

General | Behavioral Sciences | Science | Subjects | Books

All Amazon Upgrade | Amazon Upgrade | Stores | Books

Health, Mind & Body | Amazon Upgrade | Stores | Books

Professional & Technical | Amazon Upgrade | Stores | Books

Science | Amazon Upgrade | Stores | Books

All Titles | Qualifying Textbooks - Fall 2007 | Stores | Books
ASIN: 012077030X

Book Description

In this book, the editors bring together results from studies on all kinds of animals to show how thinking on many behaviors as truly cognitive processes can help us to understand the biology involved. Taking ideas and observations from the while range of research into animal behavior leads to unexpected and stimulating ideas.
A space is created where the work of field ecologists, evolutionary ecologists and experimental psychologists can interact and contribute to a greater understanding of complex animal behavior, and to the development of a new and coherent field of study.

Customer Reviews:

Don't Buy New!.......2006-12-15

I bought this book online, admittedly a bit suspicious based on reviews of the "Fast, Fun, & Easy Fabric Boxes", but the pictures looked enticing. Unfortunately, that's about all this book has going for it. The instructions, if you could call them that, are more like suggestions and sometimes very vague at best. I had a hard time figuring out whether the book or I missed a step - or three! I had to skip back and forth through the book searching for what I thought would be a logical next step. I did wind up making a lovely little handbag, but it had almost nothing to do with this book!

I have a lot of experience sewing and quilting, and not only would I not recommend this book to a beginner, I would caution anyone against buying this book if they were looking for good instruction; inspiration, yes, "how-to", no. C&T books are generally very good, and I will credit the book with lovely photos and a few basics to get you started on if you are already competent with reducing bulk in seam allowances, setting zippers, beading, and embellishments. However, this book would have been much more successful if it offered detailed and sequential instruction on just one or two basic patterns, then branched out with options on shapes, fabrics, closures, handles, etc. My suggestion... keep browsing.

Missing the point--should be projects for the beginner, but lacks detail.......2006-04-02

On first glance, this book looks like the perfect venue for an inexperienced crafter to create very functional bags. I can sew a seam, but I'm not an expert, so I purchased this book for the projects. As promised, the projects looked quite nice. However, the book itself lacks a level of detail necessary for the novice crafter to successfully complete the projects.

For instance, one of the projects is a box-type bag. While the point is to provide a guideline for creating many different bags using a single technique, the directions were confusing, there weren't enough illustrations for the 'tricky' aspects of the seaming and construction, and the directions didn't take you through a sample project with precise directions and specifications. For beginner projects, this is essential--you want to make the first project using the precise directions. Once you master the technique, THEN it's time to branch out and use your creativity.

I liked the projects in this book, but I wish the author and the editors took the time to consider their audience and not assume specific experience and knowledge of sewing. There are better books to look at--try "Mary Mulari's Accessories With Style: Quick & Clever Sewing Projects to Wear & Carry."

Books:

Books Index

Books Home

Recommended Books