Computational Aspects of the Study of Biological Macromolecules by Nuclear Magnetic Resonance Spectroscopy (Nato Science Series: A:)

Book Description

Functional imaging tools such as fMRI (functional magnetic resonance imaging), PET (positron emission tomography), EEG (electro-encephalogram), and MEG (magneto-encephalogram) allow researchers to record activity in the working brain and draw inferences about how the brain functions. This book provides a survey of theoretical and computational approaches to neuroimaging, including inferential, exploratory, and causal methods of data analysis; theories of cerebral function; and biophysical and computational models of neural nets. It also emphasizes the close relationships between different approaches, for example, between causal data analysis and biophysical modeling, and between functional theories and computational models.

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Great introduction

NMR Data Processing
Jeffrey C. Hoch , and Alan Stern
Manufacturer: Wiley-Liss
ProductGroup: Book
Binding: Hardcover

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Protein NMR Spectroscopy: Principles and Practice

ASIN: 0471039004

Book Description

NMR DATA PROCESSING

Jeffrey C. Hoch and Alan S. Stern

Nuclear Magnetic Resonance (NMR) spectroscopy is a powerful nondestructive technique for exploring the structure of matter. In recent years, NMR instrumentation has become increasingly sophisticated, and the software used to acquire and process NMR data continues to expand in scope and complexity. This software has always been difficult to understand, and, until now, it seemed likely to remain that way.

NMR Data Processing examines and explains the techniques used to process, present, and analyze NMR data. It provides a complete account of the fundamentals of spectrum analysis and establishes a framework for applying those fundamentals to real NMR data. It also details, in clear and concise language, the basic principles underlying the complex software needed to analyze the data.

Two chapters are devoted to the fundamentals and applications of discrete Fourier transform (DFT) in NMR, which was crucial to the development of modern NMR spectroscopy. A large part of the book focuses on increasingly important non-DFT methods, which obtain higher sensitivity and resolution. Other topics covered include:
* Data formats
* Processing for multidimensional experiments
* Parametric modeling of NMR signals
* Standard techniques-apodization, zero-filling, the Hilbert transform
* Artifacts-aliasing, leakage, solvent signals
* Advanced processing techniques-LP, MaxEnt, Bayesian analysis

Jeffrey C. Hoch and Alan S. Stern conclude their in-depth look at this rapidly growing field by exploring methods for analyzing processed data, including visualization, quantification, and error analysis. Readers are provided with a solid foundation for developing new methods of their own.

NMR Data Processing is an important tool for students learning basic principles for the first time, technicians troubleshooting data processing problems, and professional researchers developing new techniques. It will help all NMR users acquire a true grasp of the methods behind the process, avoid the pitfalls of misapplication and misinterpretation, and exploit the full power of NMR software.

Customer Reviews:

Great introduction.......2007-01-30

Starting with the essentials of Fourier Transform theory, this great book takes you through an enjoyable tour of modern methods of spectral analysis in NMR, highlighting the most relevant techniques with clarity in what could otherwise become a confusing array of acronyms. The book does not hesitate to invoke mathematical formulas where necessary to explain the function of the methods, but does so in the gentle style that makes the classic Numerical Recipes books so pleasant to read. Hoch and Stern have had ample experience in the field of modern spectrum analysis. Although the authors try to assist the newbie in the selection of appropriate techniques, a lot of questions still remain as to which is the optimal method for a particular problem, and a conclusion to be drawn from this book, as from the literature in general, is that some experimentation with numerical techniques is often required before the "best" method is hit upon. Unfortunately the book has aged and is ready for a second edition as new concepts such as GFT make their way into the mainstream.

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NMR Imaging in Chemical Engineering

Manufacturer: Wiley-VCH
ProductGroup: Book
Binding: Hardcover

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ASIN: 352731234X

Book Description

How to use nuclear magnetic resonance imaging in chemical engineering.
Written by the internationally recognized top experts from academia and industry, this first book dedicated to the topic provides an overview of existing methods and strategies to solve individual problems in chemical engineering. Written in a simple and lively manner and backed by various industrial examples, the book begins with a look at hardware and methods, continuing on to cover porous materials, fluids and flow of increasing complexity from different fields of Chemical Engineering, before finishing off with a review of reactors and reactions.
The result allows engineers, industrial and academic researchers and decision-makers to gain a detailed insight into the NMR toolbox, such that they can estimate the benefit of NMR imaging with regard to cost efficiency and scientific results.

Nmr Spectroscopy: Processing Strategies (Spectroscopic Techniques : An Interactive Course)

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Nmr Spectroscopy: Processing Strategies (Spectroscopic Techniques : An Interactive Course)
Peter Bigler
Manufacturer: Vch Pub
ProductGroup: Book
Binding: Paperback

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Book Description

Text for the series "Spectroscopic Techniques":
Leading software designers and teachers of spectroscopy have pooled their expertise to devise a new series "Spectroscopic Techniques: An Interactive Course". User are able to gain a better understanding of a variety of spectroscopic techniques in these step-by-step guides.

Let the experts show you new solutions to practiced problems using software provided on the interactive CD-ROM.

Information Processing in Medical Imaging: Proceedings of the 11th International Conference on Information Processing in Medical Imaging Held June 1 (Progress in Clinical & Biological Research)

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Information Processing in Medical Imaging: Proceedings of the 11th International Conference on Information Processing in Medical Imaging Held June 1 (Progress in Clinical & Biological Research)
Douglas A. Ortendahl
Manufacturer: Wiley-Liss
ProductGroup: Book
Binding: Hardcover

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The NMR program library: A library of programs for use with the IBM 370/165 computer at Daresbury Laboratory for the analysis of NMR spectra

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The NMR program library: A library of programs for use with the IBM 370/165 computer at Daresbury Laboratory for the analysis of NMR spectra
D. J Loomes
Manufacturer: Computational Science Group, Science Research Council, Daresbury Laboratory
ProductGroup: Book
Binding: Unknown Binding
ASIN: B0007ATKYK

Signal Treatment and Signal Analysis in NMR (Data Handling in Science and Technology)

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Signal Treatment and Signal Analysis in NMR (Data Handling in Science and Technology)

Manufacturer: Elsevier Science
ProductGroup: Book
Binding: Hardcover

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Book Description

Signal analysis and signal treatment are integral parts of all types of Nuclear Magnetic Resonance. In the last ten years, much has been achieved in the development of dimensional spectra. At the same time new NMR techniques such as NMR Imaging and multidimensional spectroscopy have appeared, requiring entirely new methods of signal analysis. Up until now, most NMR texts and reference books limited their presentation of signal processing to a short introduction to the principles of the Fourier Transform, signal convolution, apodisation and noise reduction. To understand the mathematics of the newer signal processing techniques, it was necessary to go back to the primary references in NMR, chemometrics and mathematics journals.

The objective of this book is to fill this void by presenting, in a single volume, both the theory and applications of most of these new techniques to Time-Domain, Frequency-Domain and Space-Domain NMR signals. Details are provided on many of the algorithms used and a companion CD-ROM is also included which contains some of the computer programs, either as source code or in executable form. Although it is aimed primarily at NMR users in the medical, industrial and academic fields, it should also interest chemometricians and programmers working with other techniques.

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Wisconsin medical physics
Kevin Franklin King
Manufacturer: Depts. of Physics, Radiology, and Medical Physics, Clinical Sciences Center, University of Wisconsin
ProductGroup: Book
Binding: Unknown Binding
ASIN: B000717AA0

Book Description

With the participation of four new co-authors, Molecular Biology of the Gene has been thoroughly updated and expanded to give comprehensive and authoritative coverage of this fast-moving field, while retaining the lively, incisive writing style for which earlier editions were famous.

Customer Reviews:

Molecular Biology of the Gene.......2002-10-25

Molecular Biology of the Gene written by James D. Watson is one of the best texts on biology of the molecular level. With ample illustrations this makes a wonderful text for students and those who want to learn more about the primary structures of proteins and the interplay between them.

Molecular genetics is but one part of the whole of biology, the nature of cells and how they divide, but this book makes an attempt to address both in a seemless fashion. Genetic code, the replication of viruses and the control of protein synthesis are all a part of this book.

I found the narrative to be straight forward and very understandable as the author makes the point in a logical and lucid manor. You will need some schooling in the biological sciences as this is not a book for the novice. This text will give the biologist of the future the rigor, the perspective, and the enthusiasm that will be needed to bridge the gap between the single cell and the complexities of higher organisms.

This is an excellent text.

Clear, Concise and Comprehensive!.......2000-01-08

This book gives a better understanding and representation of recombinant DNA procedures. All topics relevant to Molecular Biology of the Gene has been addressed in a lucid manner with excellent description and illustrations. A lot of progress had been made in this field hence. But this is a must buy for students as well as educators of molecular biology.

Human Cytogenetics: 2 Volume Set (Practical Approach Series)

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Human Cytogenetics: 2 Volume Set (Practical Approach Series)

Manufacturer: Oxford University Press, USA
ProductGroup: Book
Binding: Paperback

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ASIN: 0199638438

Book Description

Cytogenetics is concerned with matching inherited traits with the appearance, structure, and behavior of chromosomes. The first volume, Human Cytogenetics: Constitutional Analysis, covers all aspects of basic human cytogenetic study other than malignancies and acquired abnormalities. The
second volume, Human Cytogenetics: Malignant and Acquired Abnormalities, describes the techniques used to study how chromosomal rearrangements can cause malignancies.

Cancer Cytogenetics: Methods and Protocols (Methods in Molecular Biology)

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Cancer Cytogenetics: Methods and Protocols (Methods in Molecular Biology)

Manufacturer: Humana Press
ProductGroup: Book
Binding: Hardcover

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ASIN: 1588290808

Book Description

A collection of key cytogenetic and FISH techniques used by modern clinical laboratories in the genetic analysis of human malignancies. The book's practical advice and methods are suitable for use at every level of expertise, including fully established laboratories, but with a sympathetic bias towards anyone considering setting up a new cytogenetics service. Here the reader will find not only elementary tutorials on the fundamentals of human karyotypes and chromosome analysis, but also detailed discussions on how laboratories may optimally upgrade their repertoire of capabilities to include such newer complementary techniques as CGH, FISH, and M-FISH.

C. Elegans II: Monograph 33 (Cold Spring Harbor Monograph Series)

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C. Elegans II: Monograph 33 (Cold Spring Harbor Monograph Series)

Manufacturer: Cold Spring Harbor Laboratory Pr
ProductGroup: Book
Binding: Hardcover

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ASIN: 0879694882

Book Description

Studies of the cells and genes of the nematode C. elegans have become a cornerstone of current biology. A classic 1988 Cold Spring Harbor monograph, The Nematode Caenorhabditis elegans, described the basic genetics, anatomy and development of the organism. Now, in that authoritative tradition, comes C. elegans II -- not a second edition but a book that breaks new ground and defines the current status of the field, providing a detailed molecular explanation of how development is regulated and the nervous system specifies varied aspects of behavior. This volume is a must for any investigator doing worm studies but it has been written and rigorously edited to illuminate for a wider community of investigators in cell and molecular biology who should know how new knowledge of C. elegans relates to their own specialty.

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Diagnostic Molecular Pathology
Debra G. B. Leonard
Manufacturer: Saunders
ProductGroup: Book
Binding: Hardcover

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ASIN: 0721600476

Book Description

This practical guide provides information essential to understanding the significance of molecular biology and its application to everyday practice. Coverage focuses on the spectrum of currently used molecular tests in the areas of hematopathology, solid tumors, genetics, and identify testing. Examples of both molecular and cytogenetic assays demonstrate how these tests are used in today's pathology labs to detect a wide range of infectious diseases and inherited and metabolic conditions.

Presents the full range of molecular diagnostic methods from the standpoint of their clinical applications and diagnostic value.
Provides full-chapter coverage of each type of molecular testing, including genetics carcinomas sarcomas leukemias and lymphomas and identity testing.
Concisely covers all areas of molecular pathologymaking it the single source for all aspects of this field.
Features the contributions of 12 leading experts in molecular pathology.
Offers a complete introduction to molecular biology as well as common molecular methods of testing.
Focuses on test utility as well as test interpretation and significance.

With 11 additional contributors.

Heterochromatin: Molecular and Structural Aspects

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Heterochromatin: Molecular and Structural Aspects

Manufacturer: Cambridge University Press
ProductGroup: Book
Binding: Hardcover

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Book Description

Ram Verma has assembled ten distinguished contributors to survey what is currently known about the relationship of the structure of DNA to its role in the function and expression of genes. The crucial role of heterochromatin in the organization of chromosomes is thoroughly explored in this resulting landmark edited volume. Cytogeneticists and other geneticists, molecular biologists, cytologists, biochemists and their advanced students will also find this an invaluable reference source.

Molecular Cytogenetics: Protocols and Applications (Methods in Molecular Biology)

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Molecular Cytogenetics: Protocols and Applications (Methods in Molecular Biology)

Manufacturer: Humana Press
ProductGroup: Book
Binding: Hardcover

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ASIN: 1588290069

Book Description

Yao-Shan Fan and a panel of senior scientists and pioneering researchers describe in step-by-step style the leading FISH techniques and those molecular technologies beyond FISH available for diagnostic services in genetics and oncology. The methods include labeling FISH probes for DNA and RNA targets, fluorescence genotyping, CGH microarray, spectral karyotyping/multicolor FISH, and primed in situ labeling. There are also techniques for multicolor fiber FISH, multi-telomere FISH, prenatal diagnosis using maternal blood, and preimplantation diagnosis. Oncological methods include simultaneous fluorescence immunophenotyping and FISH for leukemia and lymphoma, HER2 amplification in breast cancer, and CAC/PAC for cancer cytogenetics.

Advanced Techniques in Chromosome Research

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Advanced Techniques in Chromosome Research

Manufacturer: CRC
ProductGroup: Book
Binding: Hardcover

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Book Description

Contributors detail up-to-date guidelines for using molecular techniques, cytogenetic and linkage analysis, and cellular methods, emphasizing human cells and medically relevant research. They present results of recent applications of techniques and step-by-step protocols for cloning large DNA molecu

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Intro to cell culturing, staining technique, interpretaion

Analyzing Chromosomes (Basics)
Czepulkowski
Manufacturer: BIOS Scientific Publ
ProductGroup: Book
Binding: Paperback

Biochemistry | Biological Sciences | Science | Subjects | Books

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ASIN: 1859961886

Book Description

Analysing Chromosomes is a user-friendly guide to successful techniques in the cytogenetics laboratory. Basic theory is linked with suggestions for suitable protocols. Techniques are explained in an easy-to-follow step-by-step format. The book also focuses on data interpretation and looks at possible errors and artefacts and provides appropriate trouble shooting advice.

Customer Reviews:

Intro to cell culturing, staining technique, interpretaion.......2002-01-21

This is a book of cytogenetics. (I'm a nonbio major.)
The author seems a person who supervises lab tests for hospitals.
Excellent detailed diagrams explaining mitosis and meiosis.
Looking at chromosomes thru an optical microscope with stains.
Looking at the chromosome bands and interpreting them as genetic defects,
both congenital and acquired (cancerous).
Cell culturing and staining techniques.
Has simplified catalogs of irregularities
including one entry on retinoblastoma.
The resolution of staining technology is about 4 megabases.
Introduction to some specialized higher resolution techniques.
Reading this book awakens us to the coming science-fiction future
where medical diagnosis will be based on the full genome.

Animal Genomics: Reprint of Cytogenetic and Genome Research 2003 (Cytogenetic & Genome Research)

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Animal Genomics: Reprint of Cytogenetic and Genome Research 2003 (Cytogenetic & Genome Research)

Manufacturer: S Karger Pub
ProductGroup: Book
Binding: Hardcover

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