The Structure of Biological Membranes, Second Edition

Book Description

Recent research has provided an abundance of new information on membrane biochemistry. Now more than ever, it is essential to update our current understanding of membrane structure and function to fully appreciate and apply these findings. Completely revised and updated to reflect advances in the field, The Structure of Biological Membranes, Second Edition focuses on lipids and the lipid bilayer, as well as on membrane protein structure and function, and includes a chapter on transport. It provides an integrated view of membranes as functioning units. This new edition incorporates recent advances in membrane protein structure, membrane rafts and membrane fusion. The roles of cholesterol in the biology of cells, the structures of G-protein coupled receptors, membrane lipids as modulators of membrane-bound enzymes, and viral fusion mechanisms are presented and analyzed in depth. Updating our knowledge of biological membrane structure, this second edition serves as a valuable resource for structural biologists, biophysicists, cell biologists, biochemists, and researchers involved in the pharmaceutical industry.

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good introductory work
Excellent starting for Biophysics

Biophysics
Roland Glaser
Manufacturer: Springer
ProductGroup: Book
Binding: Hardcover

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ASIN: 3540670882

Book Description

Biophysics - the science of physical principles of life itself, of biological systems - is presented here not merely as physics for biologists, but as an entirely independent subject with its own innate network of ideas and approaches. From the microscopic forces that constitute life, the intramolecular bonds and ionic interactions, to the macroscopic forces of the environment, temperature and pressure, the author presents and explains all aspects of life from a Biophysicist's point of view. Exciting biological themes such as neuronal processing and differentiation as well as current medical and environmental topics are introduced from a surprising perspective in this imaginative new textbook.

Customer Reviews:

good introductory work.......2004-09-20

This is a very thoroughly written introductory work for biophysics, an area where it is very difficult indeed to find intro-level textbooks.

Both biologists and physicists will find many new things worth exploring, and this book will certainly provide the basics for further research and study. It isn't the ten volume all-you-will-ever-want-to-know-about-biophysics, but whichever area You are starting to work with, from membrane transport to biomechanics, have a look at this book first.

Excellent starting for Biophysics.......2003-09-22

This book is written by a biologist. However, the author discussed lots of physics topics closely related to basic biological phenomena. The most important role of this book, I believe, is making the bridge between physics and biology as well as biochemistry. Untill now, most of biophyiscs text books have been a kind of biochemsitry text book like ones. This one is distingusihed from those. This is also good for biochemistry student who wants to study physical aspects of biological system beyond the scope of biochemistry. Some parts of this book might be difficult for biology and biochemistry students but surely deserves to be read.

Membrane Transport: A Practical Approach

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Membrane Transport: A Practical Approach

Manufacturer: Oxford University Press, USA
ProductGroup: Book
Binding: Paperback

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ASIN: 0199637040

Book Description

Membrane Transport is targeted towards researchers with an interest in the mechanism of solute transport across biological membranes. Its scope is broad, ranging from the techniques required to study transport itself, through the expression, purification and reconstitution of transporters, to techniques for investigation of their structures. As such, it not only proves the necessary technical grounding for newcomers to the field, but should also be of value to "old-hands" wishing to get up to date with recent developments in these areas. While some of the approaches described require sophisticated equipment (e.g. a stopped-flow fluorimeter), most of the protocols can be implemented in any well- found laboratory. Preparation of this volume comes at a time when a result of genome sequencing our knowledge of membrane transporter sequences is far outstripping our understanding of their molecular mechanisms. Our hope is that this book will help future researchers to redress this imbalance.

Moving Questions: A History of Membrane Transport and Bioenergetics

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Moving Questions: A History of Membrane Transport and Bioenergetics
Joseph D. Robinson
Manufacturer: An American Physiological Society Book
ProductGroup: Book
Binding: Hardcover

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Book Description

This book describes half a century of progress in two mainstream areas of biological research: membrane transport, initially a focus of physiologists, and oxidative phosphorylation, initially a focus of biochemists. Robinson shows how the development of new explanatory models had unexpectedly merged these inquiries into a new field, bioenergetics. In the late 1930s, explanations for the asymmetric distribution of ions between cells and their environments invoked absolute impermeabilities of the cell's surrounding membranes. But new experiments contradicted that idea and demonstrated that forming the transmembrane distributions required metabolic energy, implying the participation of active transport "pumps." Subsequent studies identified, isolated, and characterized these pumps as enzymes coupling ionic transport to the consumption of adenosine triphosphate (ATP), an "energy-rich" molecule serving as a cellular energy store. In the late 1930s oxidative phosphylation, the process of coupling ATP synthesis to oxidative metabolism, was identified. The explanatory model emerging in the next decades, however, did not follow the enzymatic precedents of known metabolic phosphorylations but rather embodied the principle that metabolic oxidations drive active transport pumps to create transmembrane distribution of ions, with these ionic asymmetries then driving ATP synthesis. It was discovered that ATP consumption can form ionic asymmetries; ionic asymmetries can drive ATP formation; and ionic asymmetries-like ATP-can also power other cellular functions.

Physical Chemistry of Membranes: An introduction to the structure and dynamics of biological membranes

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Physical Chemistry of Membranes: An introduction to the structure and dynamics of biological membranes
B. Silver
Manufacturer: Springer
ProductGroup: Book
Binding: Hardcover

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Bones: Structure and Mechanics
John D. Currey
Manufacturer: Princeton University Press
ProductGroup: Book
Binding: Hardcover

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ASIN: 0691090963

Book Description

This is a comprehensive and accessible overview of what is known about the structure and mechanics of bone, bones, and teeth. In it, John Currey incorporates critical new concepts and findings from the two decades of research since the publication of his highly regarded The Mechanical Adaptations of Bones. Crucially, Currey shows how bone structure and bone's mechanical properties are intimately bound up with each other and how the mechanical properties of the material interact with the structure of whole bones to produce an adapted structure.

For bone tissue, the book discusses stiffness, strength, viscoelasticity, fatigue, and fracture mechanics properties. For whole bones, subjects dealt with include buckling, the optimum hollowness of long bones, impact fracture, and properties of cancellous bone. The effects of mineralization on stiffness and toughness and the role of microcracking in the fracture process receive particular attention. As a zoologist, Currey views bone and bones as solutions to the design problems that vertebrates have faced during their evolution and throughout the book considers what bones have been adapted to do. He covers the full range of bones and bony tissues, as well as dentin and enamel, and uses both human and non-human examples.

Copiously illustrated, engagingly written, and assuming little in the way of prior knowledge or mathematical background, Bones is both an ideal introduction to the field and also a reference sure to be frequently consulted by practicing researchers.

ESR Spectroscopy in Membrane Biophysics (Biological Magnetic Resonance)

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ESR Spectroscopy in Membrane Biophysics (Biological Magnetic Resonance)
Marcus A. Hemminga , and Lawrence J. Berliner
Manufacturer: Springer
ProductGroup: Book
Binding: Hardcover

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ASIN: 0387250662

Book Description

Spectroscopic methods are not only important as an analytical tool, they also provide information about fundamental physical and chemical properties of molecules, the molecular and electronic structure, and the dynamic behaviour of molecules. Starting from a comprehensive quantum mechanical description, ESR Spectroscopy in Membrane Biophysics introduces the optical (IR, Raman, UV/Vis, CD, fluorescence and laser spectroscopy) and magnetic resonance (1D and 2D-NMR, ESR) techniques.

ESR Spectroscopy in Membrane Biophysics is a timely review of the increasing interest in using spin-label ESR as an alternative structural technique for NMR or X-ray diffraction. It is aimed at training an audience to learn ESR spectroscopy to determine membrane protein structures, conformational dynamics and protein-lipid interaction.

Biological Membrane Ion Channels: Dynamics, Structure, and Applications (Biological and Medical Physics, Biomedical Engineering)

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Biological Membrane Ion Channels: Dynamics, Structure, and Applications (Biological and Medical Physics, Biomedical Engineering)

Manufacturer: Springer
ProductGroup: Book
Binding: Hardcover

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ASIN: 0387333231

Book Description

Ion channels are biological nanotubes that are formed by membrane proteins. Because ion channels regulate all electrical activities in living cells, understanding their mechanisms at a molecular level is a fundamental problem in biology. This book deals with recent breakthroughs in ion-channel research that have been brought about by the combined effort of experimental biophysicists and computational physicists, who together are beginning to unravel the story of these exquisitely designed biomolecules. With chapters by leading experts, the book is aimed at researchers in nanodevices and biosensors, as well as advanced undergraduate and graduate students in biology and the physical sciences.

Neutron Scattering in Biology: Techniques and Applications (Biological and Medical Physics, Biomedical Engineering) (Biological and Medical Physics, Biomedical Engineering)

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Neutron Scattering in Biology: Techniques and Applications (Biological and Medical Physics, Biomedical Engineering) (Biological and Medical Physics, Biomedical Engineering)

Manufacturer: Springer
ProductGroup: Book
Binding: Hardcover

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ASIN: 3540291083

Product Description

The advent of new neutron facilities and the improvement of existing sources and instruments world wide supply the biological community with many new opportunities in the areas of structural biology and biological physics. The present volume offers a clear description of the various neutron-scattering techniques currently being used to answer biologically relevant questions. Their utility is illustrated through examples by some of the leading researchers in the field of neutron scattering. This volume will be a reference for researchers and a step-by-step guide for young scientists entering the field and the advanced graduate student.

Transport of Molecules across Microbial Membranes (Society for General Microbiology Symposia)

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Transport of Molecules across Microbial Membranes (Society for General Microbiology Symposia)

Manufacturer: Cambridge University Press
ProductGroup: Book
Binding: Hardcover

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ASIN: 0521772702

Book Description

This volume details the transport of molecules, large and small, across the membranes of prokaryotic and eukaryotic microbial cells. An international group of contributors unify a diverse range of phenomena with the discussion of the signal peptides that target proteins to particular destinations, and the role of chaperonins. Topics covered include secretion of proteins out of the bacterial cell by Type I, II, and III mechanisms, including the newly recognized bacterial signal recognition pathway in Type II; passage across internal membranes of eukaryotic proteins, whether destined for secretion or en route to internal organelles such as chloroplasts and peroxisomes; how bacteria obtain energy required for solute uptake; the role of phosphorylation and evolutionary relationships of the proteins involved; and efflux pumps for toxic substances in bacterial, animal, and plant cells.

Book Description

Sahelian West Africa has recovered from the disastrous droughts of the 1970s and 1980s. People have learned to adapt to risk and uncertainty in fragile dryland environments. They, as well as global change scientists, are worried about the impact of climate change on these West African drylands. What do the experiences of the last thirty years say about the preparedness for higher temperatures, lower rainfall, and even more variability? Detailed studies on Dryland West Africa as a whole, and on Burkina Faso, Mali and Northern Ghana in particular show an advanced coping behaviour and increased adaptation, but also major differences in vulnerability and coping potential. Climate change preparedness programmes have only just started and require more robust support, and more specific social targeting, for a population which is rapidly growing, even more rapidly urbanising, and further integrating in a globalised economy.

This book is the first of its kind with a comprehensive analysis of climate change experiences in West African drylands, with attention for pathways of change and the diversity of adaptation options available. This book is of interest to scientists studying global and climate change, especially dealing with issues of adaptation. Social scientists, economists, geographers and policy makers concerned with West Africa should also read this book.

The Impact of Climate Change on the United States Economy

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The Impact of Climate Change on the United States Economy

Manufacturer: Cambridge University Press
ProductGroup: Book
Binding: Paperback

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ASIN: 0521607698

Book Description

Understanding the impacts of climate change on economic behaviour is an important aspect of deciding when to take policy actions to prevent or mitigate its consequences. This book applies advanced new economics methodologies to assess impacts on potentially vulnerable aspects of the US economy: agriculture, timber, coastal resources, energy expenditure, fishing, outdoor recreation. It is intended to provide improved understanding of key issues raised in the recent Intergovernmental Panel on Climate Change (IPCC) reports. It concludes that some climate change may produce economic gains in the agriculture and forestry sectors, whereas energy, coastal structures, and water sectors may be harmed. The book will serve as an important reference for the scientific, economic, and policy community, and will also be of interest to natural resource/environmental economists as an example of economic valuation techniques. The volume will clearly be of main importance to researchers and policymakers in the US, but will also be influential as a model for assessment of impacts on economies worldwide.

Climate Change 2001: Synthesis Report: Third Assessment Report of the Intergovernmental Panel on Climate Change

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Climate Change 2001: Synthesis Report: Third Assessment Report of the Intergovernmental Panel on Climate Change

Manufacturer: Cambridge University Press
ProductGroup: Book
Binding: Paperback

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ASIN: 0521015073

Book Description

The Climate Change 2001 volumes of the Third Assessment Report of the IPCC provide the most comprehensive assessment of climate change since its second report, Climate Change 1995. This Synthesis Report gives a comprehensive summary of the main points of the three separate volumes of the Report: The Scientific Basis; Impacts, Adaptation, and Vulnerability; and Mitigation.

Apocalypse Soon?: Wagering on Warnings of Global Catastrophe

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Apocalypse Soon?: Wagering on Warnings of Global Catastrophe
Stephen F. Haller
Manufacturer: McGill-Queen's University Press
ProductGroup: Book
Binding: Hardcover

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Changing by Degrees: The Potential Impacts of Climate Change in the East Midlands (Ashgate Studies in Environmental Policy and Practice)

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Changing by Degrees: The Potential Impacts of Climate Change in the East Midlands (Ashgate Studies in Environmental Policy and Practice)
Jim Kersey , Rob Wilby , and Paul Fleming
Manufacturer: Ashgate Pub Ltd
ProductGroup: Book
Binding: Hardcover

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ASIN: 075461140X

Climate Change 2001: Mitigation: Contribution of Working Group III to the Third Assessment Report of the Intergovernmental Panel on Climate Change

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Climate Change 2001: Mitigation: Contribution of Working Group III to the Third Assessment Report of the Intergovernmental Panel on Climate Change

Manufacturer: Cambridge University Press
ProductGroup: Book
Binding: Paperback

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ASIN: 0521015022

Book Description

Some issues addressed in this Working Group III volume are mitigation of greenhouse gas emissions, managing biological carbon reservoirs, geo-engineering, costing methods, and decision-making frameworks.

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Climate Change and Adaptation

Manufacturer: Earthscan Publications Ltd.
ProductGroup: Book
Binding: Hardcover

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Book Description

Many parts of the developing world are subject to variable and extreme climate, the impacts of which impede development and point to the need to improve the understanding and management of climate risks. These needs are being amplified by human-caused climate change. The Intergovernmental Panel on Climate Change (IPCC) concluded in its 2001 report that much of the developing world is highly vulnerable to adverse impacts from climate change. But the IPCC also concluded that the vulnerabilities of developing countries are too little studied and too poorly understood to enable determination of adaptation strategies that would be effective at reducing risks. Climate Change and Adaptation and its companion volume Climate Change and Vulnerability, resulting from the work of the Assessments of Impacts and Adaptations to Climate Change (AIACC) project launched by the IPCC in 2002, are the first to provide a comprehensive investigation of the issues at stake.

Climate Change and Adaptation covers current practices for managing climate risks to food security, water resources, livelihoods, human health and infrastructure, deficits between current practices and needs for effective management of climate risks, the changing nature of the risks due to human-caused climate change, strategies for adapting to climate change to lessen the risks, and the need to integrate these strategies into development planning and resource management. The book also identifies obstacles to effective adaptation and explore measures needed to create conditions that are favorable to climate change adaptation. The findings and lessons will be of use to policymakers and managers responsible for understanding and avoiding potentially adverse effects from climate change on sustainable development, food security, agriculture, water resources, forests, fisheries, grazing lands, biodiversity and public health. Citizen activists who are concerned about reducing the threats from climate change to the poor, sustainable development, biodiversity, and sensitive environmental systems and resources will learn about options for management of the threats.

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Climate Change and Vulnerability

Manufacturer: Earthscan Publications Ltd.
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Binding: Hardcover

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Climate Change Vulnerability and Adaptation: Two Volume Set

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Climate Change Vulnerability and Adaptation: Two Volume Set

Manufacturer: Earthscan Publications Ltd.
ProductGroup: Book
Binding: Paperback

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Book Description

This two volume set consists of one copy of each Climate Change and Vulnerability and Climate Change and Adaptation, which are also sold singly.

Many parts of the developing world are subject to variable and extreme climate, the impacts of which impede development and point to the need to improve the understanding and management of climate risks. These needs are being amplified by human-caused climate change. The Intergovernmental Panel on Climate Change (IPCC) concluded in its 2001 report that much of the developing world is highly vulnerable to adverse impacts from climate change. But the IPCC also concluded that the vulnerabilities of developing countries are too little studied and too poorly understood to enable determination of adaptation strategies that would be effective at reducing risks. These authoritative volumes, resulting from the work of the Assessments of Impacts and Adaptations to Climate Change (AIACC) project launched by the IPCC in 2002, are the first to provide a comprehensive investigation of the issues at stake.

Climate Change: Science, Impacts and Policy

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Climate Change: Science, Impacts and Policy

Manufacturer: Cambridge University Press
ProductGroup: Book
Binding: Hardcover

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