Genomic Imprinting and Uniparental Disomy in Medicine: Clinical and Molecular Aspects

Book Description

Eric Engel and Stylianos Antonarakis have written the most authoritative and vital reference on molecular and clinical aspects of uniparental disomy (UPD) and genomic imprinting to date. Genomic Imprinting and Uniparental Disomy in Medicine features comprehensive overviews of a multitude of genetic disorders linked to UPD, with a strong emphasis on clinical consequences. This book will provide readers with the tools necessary to identify and treat diseases associated with nontraditional chromosomal inheritance.

Genomic Imprinting and Uniparental Disomy in Medicine features handy tables summarizing clinical phenotypes and chromosomal involvement in UPD, as well as clear illustrations on imprinting mechanisms and diagnostic testing. This authoritative, completely up-to-date practical reference will be useful for any clinical geneticist, genetic counselor, physician, or researcher encountering patients with such disorders or studying complex disease mechanisms.

Customer Reviews:

Great Reference.......2003-07-25

"...a thorough review...a great...reference..." (Journal of Genetic Counseling, Vol. 12, No. 3, June 2003)

Genomic Imprinting and Kinship (The Rutgers Series in Human Evolution, edited by Robert Trivers, Lee Cronk, Helen Fisher, and Lionel Tiger)

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Genomic Imprinting and Kinship (The Rutgers Series in Human Evolution, edited by Robert Trivers, Lee Cronk, Helen Fisher, and Lionel Tiger)
David Haig
Manufacturer: Rutgers University Press
ProductGroup: Book
Binding: Paperback

Genetics | Evolution | Science | Subjects | Books

General | Evolution | Science | Subjects | Books

General | Science | Subjects | Books

ASIN: 081353027X

Genomic Imprinting (Cytogenetic and Genomic Research)

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Genomic Imprinting (Cytogenetic and Genomic Research)

Manufacturer: S Karger Pub
ProductGroup: Book
Binding: Paperback

Genetics | Evolution | Science | Subjects | Books

Genetics | Basic Science | Medicine | Subjects | Books

General | Medicine | Subjects | Books

Genomic Imprinting (Frontiers in Molecular Biology)

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Genomic Imprinting (Frontiers in Molecular Biology)

Manufacturer: Oxford University Press, USA
ProductGroup: Book
Binding: Hardcover

Biochemistry | Biological Sciences | Science | Subjects | Books

Genetics | Evolution | Science | Subjects | Books

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Book Description

Genomic imprinting, the differential marking of genes inherited from paternal and maternal sources, has been recognized since the late 1970s and is known to be involved in several inherited diseases. However, it is only very recently that questions surrounding the mechanisms of genomic imprinting have begun to be answered. This volume reviews the latest exciting developments, with full citations of all of the key bibliography. It also discusses the major unanswered questions in this field and outlines directions for future research. Topics covered in Genomic Imprinting include: the role of DNA methylation in mammalian development; developmental regulation of imprinting by DNA methylation; imprinting at the mouse and human IGF2R loci; function and epigenetic modification of the imprinted H19 gene; the imprinted insulin-like growth factor 2 gene; consequences of genomic imprinting for fetal development; genomic imprinting in the mouse; systematic approaches for the identification of imprinted genes; genomic imprinting as a developmental process disturbed in cancer; imprinting in the PraderWilli/Angelman syndrome region on human chromosome 15; convergent themes in X chromosome inactivation and autosomal imprinting; and evolutionary theories of genomic imprinting.

Genomic Imprinting: An Interdisciplinary Approach (Results and Problems in Cell Differentiation)

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An important work on an important problem

Genomic Imprinting: An Interdisciplinary Approach (Results and Problems in Cell Differentiation)

Manufacturer: Springer-Verlag Telos
ProductGroup: Book
Binding: Hardcover

Biochemistry | Biological Sciences | Science | Subjects | Books

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General | Science | Subjects | Books

Natural History | Nature & Ecology | Science | Subjects | Books

Biochemistry | Basic Science | Medicine | Subjects | Books

Genetics | Basic Science | Medicine | Subjects | Books

General | Medicine | Subjects | Books

Book Description

This book provides an unrivalled in-depth treatise of genomic imprinting, a phenomenon which plays a vital role in many biological processes in developmental biology, evolution and human diseases and genetics. The reason for this broad range of influence derives from the fact that genomic imprinting shields a number of important genes from the full effects of Mendelian inheritance. The importance of this surprising observation, which was discovered less than two decades ago, has been only slowly recognized. The reason for this may be that genomic imprinting is a difficult concept to understand. This book aims at providing interesting, entertaining and detailed information for any scientist, irrespective of their particular field of study.

Customer Reviews:

An important work on an important problem.......2000-11-11

This is an excellent and thorough work on an interesting and important problem. All aspects of genomic imprinting are discussed in both mammalian and other systems. Well organized. If you want to learn about imprinting, this is the best place to start. Reading this book has really expanded my knowledge of this subject, and I recommend it for everyone interested in genetics.

Genomic Imprinting: Causes and Consequences

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Genomic Imprinting: Causes and Consequences

Manufacturer: Cambridge University Press
ProductGroup: Book
Binding: Hardcover

Genetics | Evolution | Science | Subjects | Books

General | Evolution | Science | Subjects | Books

Natural History | Nature & Ecology | Science | Subjects | Books

Genetics | Basic Science | Medicine | Subjects | Books

General | Medicine | Subjects | Books

General | Reference | Medicine | Subjects | Books

Reference | Medicine | New & Used Textbooks | Stores | Books

Nursing | Medicine | New & Used Textbooks | Stores | Books

Book Description

Genomic imprinting results in the preferential expression of one gene, depending on the parent of origin, and it is associated with several disease syndromes in humans. This book covers a wealth of research material on chromatin structure, epigenetics, clinical genetics, developmental biology, cancer, hypotheses of evolution, and the molecular basis of the imprinting process, which will help explain not only the mechanisms of genomic imprinting, but also its biological and medical consequences.

Genomic Imprinting: Methods and Protocols (Methods in Molecular Biology)

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Genomic Imprinting: Methods and Protocols (Methods in Molecular Biology)

Manufacturer: Humana Press
ProductGroup: Book
Binding: Hardcover

Genetics | Evolution | Science | Subjects | Books

Research | Education | Science | Subjects | Books

Methodology & Statistics | Experiments, Instruments & Measurement | Science | Subjects | Books

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All Titles | Qualifying Textbooks - Fall 2007 | Stores | Books
ASIN: 089603741X

Book Description

Andrew Ward and a team of experienced researchers have brought together a collection of optimized classic and vanguard techniques for the identification and analysis of imprinted genes. Protocols are included for identifying and cloning imprinted genes, for analyzing imprinted gene expression, for the study of DNA methylation and methylation-sensitive DNA-binding proteins, and for examining chromatin structure. There are also methods for the manipulation of mouse embryos to produce monoparental embryos and embryonic stem cells, and for the generation of transgenic mice with BAC, PAC,and YAC constructs. Each technique is described in step-by-step detail to ensure successful results.

Angelman syndrome: An entry from Thomson Gale's
<i>Gale Encyclopedia of Genetic Disorders, 2nd ed.</i>

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Angelman syndrome: An entry from Thomson Gale's Gale Encyclopedia of Genetic Disorders, 2nd ed.
Jennifer, MS, CGC Roggenbuck
Manufacturer: Thomson Gale
ProductGroup: Book
Binding: Digital
ASIN: B000M5B0C0

Book Description

Information on many genetic disorders, and the frequent new findings on them, has been extremely difficult to come by—until now. The “Gale Encyclopedia of Genetic Disorders” addresses the need for current, hard-to-find facts on emerging discoveries. The two-volume Encyclopedia, presented in a single alphabetical sequence, provides clear, complete information on genetic disorders, including conditions, tests, procedures, treatments and therapies, in articles that are both comprehensive and easy to understand, in language accessible to laypersons. The articles are arranged in a standardized format for quick comparison and ease of use, while non-disorder topics are covered in detail with extended entries. Students will want to consult the “Gale Encyclopedia of Genetic Disorders” for useful information on a range of well known disorders, including Down Syndrome, Trisomy, Hemophilia and Tourette Syndrome, and rarely seen diseases such as Meckel Syndrome, Neuraminidase Deficiency and Phenylketonuria.

Computational Biology and Bioinformatics: a tinge of Indian spice.(Editorial): An article from: Bioinformation

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Computational Biology and Bioinformatics: a tinge of Indian spice.(Editorial): An article from: Bioinformation
N. Srinivasan
Manufacturer: Thomson Gale
ProductGroup: Book
Binding: Digital

Bioinformatics | Biological Sciences | Science | Subjects | Books

Book Description

This digital document is an article from Bioinformation, published by Thomson Gale on January 1, 2006. The length of the article is 3521 words. The page length shown above is based on a typical 300-word page. The article is delivered in HTML format and is available in your Amazon.com Digital Locker immediately after purchase. You can view it with any web browser.

Citation Details
Title: Computational Biology and Bioinformatics: a tinge of Indian spice.(Editorial)
Author: N. Srinivasan
Publication: Bioinformation (Magazine/Journal)
Date: January 1, 2006
Publisher: Thomson Gale
Page: 105(5)

Article Type: Editorial

Distributed by Thomson Gale

Imprinting: An entry from Thomson Gale's
<i>Gale Encyclopedia of Genetic Disorders, 2nd ed.</i>

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Imprinting: An entry from Thomson Gale's Gale Encyclopedia of Genetic Disorders, 2nd ed.
Maria, PhD Basile
Manufacturer: Thomson Gale
ProductGroup: Book
Binding: Digital
ASIN: B000M5B1QA

Book Description

Book Description

This widely used, highly readable introduction to structural analysis is specifically designed to support the laboratory work of undergraduates in structural geology courses. Throughout the book, a geologic map from a mythical site, the Bree Creek Quadrangle, is used to help students analyze various aspects of the geologic structures exposed within this quadrangle, and ultimately to combine these analyzes into a grand synthesis.Guided by students ' and instructors ' suggestions, the authors have refined several exercises and added new ones for this third edition. In addition, every figure has been redrafted to improve clarity, and the Bree Creek Quadrangle map has been compiled onto a single fold-out sheet. An instructor 's manual is available on request from the publisher to assist the laboratory instructor in the use of the book.

Customer Reviews:

Poor undergrad textbook.......2003-10-16

Examples are poorly laid out in the text, and the questions seldom follow from what has been shown in the text. Not a useful learning tool at all.

Structural Analysis & Synthesis: A Laboratory Course in Stru.......2001-07-11

This lab manual was required for our structural geology course given at the California State University, Dominguez Hills. In general, the book is not well laid out and there are too few problems to work. In order to become proficient one must work many types of problems. The author does not give enough examples of how to solve problems using both graphical then mathematical techniques. For example, a three-point problem can be solved by graphical or mathematical methods. Additionally, the book requires the reader to move between pages to extract the necessary information to solve a problem. This makes the book appear vague or confusing at times. The book is weak in areas that are of prime importance to geologists such as 3 point problems, thickness problems, out crop patterns, etc. These areas are important because they are used regularly in the interpretation of geology. Additionally, these problems are also found on many Registered Geology examination given by various states.

This was my lab book.......2000-05-26

BAD. I had to use this for lab this quarter. The problems were on one page, the information and maps to work it were sometimes two pages prior to, or after it. Bad layout. Far too much page flipping. This book also didn't give very good examples, in such that they would give a very elementary example, and give significantly more complex problems to work, without any farther explaination. This area of Geology is difficult enough for us poor undergrads coming up without having this book to throw us off track.

Efficient Computation of Nonlinear Transient Structural Synthesis for Seismic Isolation

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Efficient Computation of Nonlinear Transient Structural Synthesis for Seismic Isolation

Manufacturer: Storming Media
ProductGroup: Book
Binding: Spiral-bound
ASIN: 1423545028

Product Description

This is a NAVAL POSTGRADUATE SCHOOL MONTEREY CA report procured by the Pentagon and made available for public release. It has been reproduced in the best form available to the Pentagon. It is not spiral-bound, but rather assembled with Velobinding in a soft, white linen cover. The Storming Media report number is A119263. The abstract provided by the Pentagon follows: A method of structural synthesis is presented using a recursive computational process. A structure can be modeled entirely linearly, with localized nonlinearities included as synthesized forces. The method allows retention of only the degrees of freedom (DOF) of interest, including, at a minimum, the DOF at which nonlinearities are applied. The method is illustrated using an n-degree of freedom finite element model of a simple structure. The method is shown to adjust the response of the system based on addition of a nonlinear base isolator. Finally, the method is compared to MATLAB's ODE45 function as a measure of accuracy and efficiency. The method is theoretically exact, and results in order of magnitude decreases in computational time for modification analysis.

Trends in Computerized Structural Analysis and Synthesis

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Trends in Computerized Structural Analysis and Synthesis

Manufacturer: Pergamon Press
ProductGroup: Book
Binding: Unknown Binding

Alternative approximation concepts for space frame synthesis (SuDoc NAS 1.26:172526)

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Alternative approximation concepts for space frame synthesis (SuDoc NAS 1.26:172526)
Robert V. Lust
Manufacturer: National Aeronautics and Space Administration, Langley Research Center
ProductGroup: Book
Binding: Unknown Binding
ASIN: B00010L6H0

Approximation concepts for efficient structural synthesis (NASA contractor report ; NASA CR-2552)

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Approximation concepts for efficient structural synthesis (NASA contractor report ; NASA CR-2552)
Lucien André Schmit
Manufacturer: For sale by the National Technical Information Service
ProductGroup: Book
Binding: Unknown Binding

Component mode synthesis and large deflection vibration of complex structures final report for the period ended January 31, 1987 (SuDoc NAS 1.26:181290)

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Component mode synthesis and large deflection vibration of complex structures final report for the period ended January 31, 1987 (SuDoc NAS 1.26:181290)
Chuh Mei
Manufacturer: National Aeronautics and Space Administration National Technical Information Service, distributor
ProductGroup: Book
Binding: Unknown Binding
ASIN: B00010OLC2

Development of a probabilistic dynamic synthesis method for the analysis of nondeterministic structures (SuDoc NAS 1.15:208473)

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Development of a probabilistic dynamic synthesis method for the analysis of nondeterministic structures (SuDoc NAS 1.15:208473)
A. M. Brown
Manufacturer: National Aeronautics and Space Administration, Marshall Space Flight Center National Technical Information Service, distributor
ProductGroup: Book
Binding: Unknown Binding
ASIN: B00010ZY0K

Dynamic analysis of structures with random properties by component mode synthesis,

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Dynamic analysis of structures with random properties by component mode synthesis,
T. K Hasselman
Manufacturer: Society of Automotive Engineers
ProductGroup: Book
Binding: Unknown Binding

Dynamic model synthesis using analysis of structural systems by component mode synthesis

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Dynamic model synthesis using analysis of structural systems by component mode synthesis
Edwin Jordan Gooze
ProductGroup: Book
Binding: Unknown Binding

Experimental modal analysis and dynamic component synthesis (AFWAL-TR)

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Experimental modal analysis and dynamic component synthesis (AFWAL-TR)
Randall J Allemang
Manufacturer: Flight Dynamics Laboratory, Air Force Wright Aeronautical Laboratories, Air Force Systems Command
ProductGroup: Book
Binding: Unknown Binding
ASIN: B000725RPO

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