Toll and Toll-Like Receptors:: An Immunologic Perspective (Molecular Biology Intelligence Unit)

Book Description

Until recently innate immunity was viewed as the poorer relative of the sophisticated adaptive immune response. We now know, however, that these ‘higher’ immune responses are actually underpinned by an elegantly hewn system of innate immune surveillance. Discovered first by developmental biologists, again by immunologists, and even by sociologists, Toll receptors have revolutionized our understanding of innate immunology. Although a small part of a complex system, Toll receptor biology compels us to revisit existing models of self – non-self recognition.

Book Description

The book reviews the current experimental and theoretical knowledge of the synergism between modern physics, soft condensed matter and biology, presenting a thorough discussion of the relative role of the various fundamental interactions in such systems: electrostatic, hydrophobic, steric, conformational, van der Waals, etc. These competing interactions influence the form and topology of soft and biological matter, like polymers and proteins, leading to hierarchical structures in self-assembling systems and folding patterns sometimes described in terms of chirality, braids and knots. Finally, the competing interactions influence various bioprocesses like genetic regulation and biological evolution taking place in systems like biopolymers, macromolecules and cell membranes.
The authors include theoretical physicists, soft condensed matter experimentalists, biological physicists, and molecular biologists - all leaders in their respective fields. Aside from the need to gain new, fundamental insights, the subject area is also of great importance for many applications, in that self-assembly and hierarchical assembly are important features to achieve functionality on multiple length scales. Applications range from the nanoscopic (e.g., biomolecular material and copolymeric mesophases) to the microscopic (all organic microelectronics) to the macroscopic (high-performance structural composites).

Chemical Probes in Biology Science at the Interface of Chemistry, Biology and Medicine (NATO Science Series II: Mathematics, Physics and Chemistry)

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Chemical Probes in Biology Science at the Interface of Chemistry, Biology and Medicine (NATO Science Series II: Mathematics, Physics and Chemistry)

Manufacturer: Springer
ProductGroup: Book
Binding: Hardcover

Biochemistry | Biological Sciences | Science | Subjects | Books

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ASIN: 1402017693

Book Description

The field of Bio-organic Chemistry or Chemical Biology, as it it also called, constitutes a highly interdisciplinary branch of chemistry, beyond the traditional pathways in which chemists and biologists have been working in the past. The topics covered in this book include inter alia: anticancer agents, antioxidants, chemotaxis, carbohydrates, DNA detection and delivery, enzyme structure, enzyme assisted syntheses, fluorescent probes, gene therapy, genomics, inositol phospholipids, inositol phosphates, multivalent ligands, organic syntheses, oxidative stress, photoaffinity labeling techniques, natural products - syntheses and biological activities, phospholipases, proteomics, receptors such as tyrosine kinases, signal transduction phenomena, x-ray crystallography and many more. The book represents an excellent survey of the current stete of the art in an exciting area of interdisciplinary science and supplies an incentive for increased cooperation in Science at the Interface of Chemistry, Biology and Medicine.

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Chemistry and physics of interfaces--II

Manufacturer: American Chemical Society Publications
ProductGroup: Book
Binding: Unknown Binding

Computer Simulations of Surfaces and Interfaces (NATO Science Series II: Mathematics, Physics and Chemistry)

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Computer Simulations of Surfaces and Interfaces (NATO Science Series II: Mathematics, Physics and Chemistry)

Manufacturer: Springer
ProductGroup: Book
Binding: Paperback

Modeling & Simulation | Computer Science | Computers & Internet | Subjects | Books

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ASIN: 1402014643

Book Description

Studies of surfaces and interactions between dissimilar materials or phases are vital for modern technological applications. Computer simulation methods are indispensable in such studies and this book contains a substantial body of knowledge about simulation methods as well as the theoretical background for performing computer experiments and analyzing the data.

The book is self-contained, covering a range of topics from classical statistical mechanics to a variety of simulation techniques, including molecular dynamics, Langevin dynamics and Monte Carlo methods. A number of physical systems are considered, including fluids, magnets, polymers, granular media, and driven diffusive systems. The computer simulation methods considered include both standard and accelerated versions. The simulation methods are clearly related to the fundamental principles of thermodynamics and statistical mechanics.

From Physics to Biology: The Interface between Experiment and Computation: Bifi 2006 II International Congress (AIP Conference Proceedings)

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From Physics to Biology: The Interface between Experiment and Computation: Bifi 2006 II International Congress (AIP Conference Proceedings)

Manufacturer: American Institute of Physics
ProductGroup: Book
Binding: Hardcover

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Book Description

All papers in this volume were peer-reviewed. The BIFI2006 Conference represents an interactive forum for physicists, chemists, biologists, and mathematicians for sharing ideas as well as adressing recent advances in the frontier between physics and biology. Current challenges in molecular and cell biology, biomedicine, and biotechnology require the interdisciplinary collaborative effort of theoretical and experimental researchers benefiting from the interplay between the latest computational and experimental developments. There were three main topics at the conference: nucleic acids, proteins and peptides, and collective behavior of biomolecules. This volume includes papers on: protein folding, nucleic acid structure, ligand binding, proteomics, network dynamics and topology, cell signaling, collective behavior, biomolecular modeling, systems biology, and biophysical computational methods.

Fundamentals of Interface and Colloid Science, Volume II: Solid-Liquid Interfaces (Fundamentals of Interface and Colloid Science)

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Fundamentals of Interface and Colloid Science, Volume II: Solid-Liquid Interfaces (Fundamentals of Interface and Colloid Science)
J. Lyklema
Manufacturer: Academic Press
ProductGroup: Book
Binding: Hardcover

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Fundamentals of Interface and Colloid Science, Volume I: Fundamentals (Fundamentals of Interface and Colloid Science)

ASIN: 0124605249

Book Description

Interface and colloid science is an important, though often under-valued, branch of science. It has applications and ramifications in domains as disparate as agriculture, mineral dressing, oil recovery, chemical industry, biotechnology, medical science, and many more. Proper application of interface and colloid science requires factual knowledge and insight into the many basic laws of physics and chemistry upon which it is based. Fundamentals of Interface and Colloid Science is the first book to cover this field in the depth neccessary to be a valuable reference and an excellent textbook.
From the beginning to the end of the book, systems of growing complexity are treated gradually. The presentation is particularly suited to emphasize that interfaces are not autonomous phases. As a rule, interfacial properties can be varied only by changing the adjoining phases, so that the properties of these bulk phases must be understood first. The text also recognizes common principles behind a variety of phenomena, and helps the reader to understand them and to develop and improve processes. The systematic treatment of the material in the book makes this clear, and makes the text itself an important contribution to the field.

Key Features
* Systematic treatment of information
* An excellent addition to volume I
* Two chapters contributed by other experts in the field
* Uses a deductive approach to increase the order of complexity
* Written by a leading expert in the field
* Two chapters contributed by other outstanding scientists
* Uses a systematic and deductive approach
* First comprehensive review of the topic

Magnetic Resonance in Colloid and Interface Science (NATO Science Series II: Mathematics, Physics and Chemistry)

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Magnetic Resonance in Colloid and Interface Science (NATO Science Series II: Mathematics, Physics and Chemistry)

Manufacturer: Springer
ProductGroup: Book
Binding: Paperback

Analytic | Chemistry | Science | Subjects | Books

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Research | Education | Science | Subjects | Books

Methodology & Statistics | Experiments, Instruments & Measurement | Science | Subjects | Books

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ASIN: 1402007876

Book Description

Magnetic resonance techniques are especially interesting in the study of colloids and interfaces due to their unique ability to elucidate structure, dynamics and function at the atomic and molecular level. This book illustrates the most up to date applications of innovative NMR and EPR techniques, including magnetic resonance imaging and microscopy, to gas-solid and liquid-solid interfaces, organic and biological surfaces, microemulsions, liquid crystals, membranes, structure and dynamics of polymers and micellar systems, and diffusion in heterogeneous systems.

A compendium of advanced NMR and EPR techniques and a state of the art description of the power of advanced new methodologies for the study of molecular dynamics and interfaces.

Nanoscale Structure and Assembly at Solid-Fluid Interfaces: Volume I: Interfacial Structures versus Dynamics, Volume II: Assembly in Hybrid and Biological ... (Nanostructure Science and Technology)

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Nanoscale Structure and Assembly at Solid-Fluid Interfaces: Volume I: Interfacial Structures versus Dynamics, Volume II: Assembly in Hybrid and Biological ... (Nanostructure Science and Technology)

Manufacturer: Springer
ProductGroup: Book
Binding: Hardcover

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ASIN: 1402078102

Book Description

All of us have read about the vast potential inherent in nanotechnology and the exciting impact it has had in changing our lifestyle in the 21st century. One of the basic issues confronting us is how to fabricate devices or materials on the nano scale. What is the basic physics governing the formation of nano phases? How can biological systems inspire us to formulate nano scale architectures, in the way nature has always done and continues to do? These are two main areas of focus in this book.
The aim of this reference is to take us to the root of these issues: the solid-fluid interfacial structures and the basic interactions between structural units that determine the kinetics of nano particles and assembly formation, and subsequently the resulting structures and functionalities of the nano phases and devices. By taking a fresh look at the novel nano structure engineering and surface probing technologies from a global viewpoint of fundamental principles, the two volumes of this book direct our focus from the macroscopic phase to the nano structures ranging from inorganic to bio nano materials. Featuring contributions from a number of international experts in the related fields, this book offers a comprehensive and synergistic look into these challenging issues in terms of theoretical modeling, computer simulations, advanced surface probing and fabrication and interface characterizations. The book also provides a link to the nanostructure engineering of some novel materials playing an important role in advancing technologies in this field.
Volume I focuses on both the theoretical and experimental aspects of crystal surfaces and solid-fluid interfacial structures, the effect of ordering and disordering of the interfacial molecules on the kinetics of crystalline matter, and in particular on the nano crystalline phase and the formation of self-organized nanofiber networks. Expertly written chapters expand the existing knowledge on surface/interfacial structures associated with bulk phases to the micro/nano structural domain, presenting examples of the characterization and manipulation of self-organized nano structures. The subject matter covers also the principles and technologies concerning nano phases, surface/interface structure formation and characterization, and fabrication.
Volume II is devoted to the assembly of bio-related nano structures and hybrid nano materials and systems. The part on bio-related nanostructures focuses on the aggregation and pattern formation of protein molecules, or biomaterials in the bulk and on the surface of designated substrates. The way to control the process of biomineralization, biological matrices, hierarchical structures and other bio-related materials by relying on robust methods, such as templating, AFM, Chemoselective Ligation, scanning probe nanolithography will also be treated in detail. In addition, innovative techniques to engineer complex nano structures such as molecular design and molecular self assembly are highlighted.

Particle Physics and Cosmology: The Interface: Proceedings of the NATO Advanced Study Institute on Particle Physics and Cosmology: The Interface Cargèse, ... II: Mathematics, Physics and Chemistry)

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Particle Physics and Cosmology: The Interface: Proceedings of the NATO Advanced Study Institute on Particle Physics and Cosmology: The Interface Cargèse, ... II: Mathematics, Physics and Chemistry)

Manufacturer: Springer
ProductGroup: Book
Binding: Paperback

Astronomy | Astronomy | Science | Subjects | Books

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ASIN: 1402031599

Book Description

The school introduces the experimental and theoretical particle physics background underlying several aspects of cosmology: matter anti-matter asymmetry, dark matter, the acceleration of the expansion, the 3K Cosmological Background Radiation, the geometry of the universe. The theoretical lectures offer reviews by experts on topics which include the limits of the standard model, a description of the neutrino mass, supersymmetry, leptogenesis/baryogenesis, scalar fields, and extra-dimensions. The status experimental observations in particle physics and astrophysics (CP violation, neutrino oscillations, dark matter, 3K radiation) is also covered.

Physical Chemistry of Interfaces and Nanomaterials II: 6-8 August 2003 San Diego, California, USA (Proceedings of Spie Volume 5223)

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Physical Chemistry of Interfaces and Nanomaterials II: 6-8 August 2003 San Diego, California, USA (Proceedings of Spie Volume 5223)

Manufacturer: SPIE-International Society for Optical Engine
ProductGroup: Book
Binding: Paperback

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