Gold and Silver Staining: Techniques in Molecular Morphology (Advances in Pathology, Microscopy, & Molecular Morphology)

Book Description

Immunogold silver staining is one of the most sensitive techniques available for visualizing the location of antibodies and nucleotide probes that have been bounded to specific antigens or to nucleotide sequences. As gold and silver staining continues to advance research in molecular morphology, this book presents the information you need to know about the various staining methods, their useful applications, and the advantages and drawbacks of each process. Gold and Silver Staining: Techniques in Molecular Morphology provides a timely description of approaches, methods, protocols, and applications. The contributors cover the latest developments and a wide range of applications from highly sensitive detection of antigens to single copy detection of DNA and RNA. Some of the authors are "living legends" in the field and bring their expertise and experience to this fine collaboration. Written in one consistent style, each chapter includes a concise, but comprehensive introduction, step-by-step protocols with technical hints, and a discussion of results and critical steps. What differentiates this book from all others like it, is the status of the editors, who have worked on this technique from its inception and have produced innumerable publications on the topic. The other distinguishing feature is that all of the contributors are amongst the absolute foremost leaders from the United States and Europe. Gold and Silver Staining: Techniques in Molecular Morphology presents a complete overview and detailed descriptions of this technique that allows the visualization of molecules that have never been localized before and with hitherto unknown sensitivity. Not only does this book provide an excellent review of this field, but it also serves as a lab manual for those who want to carry out this technique in their laboratory and clinical work. Armed with this information, advances in this powerful field of research will ensue.

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Genetic Response to Metals
Sarkar
Manufacturer: CRC
ProductGroup: Book
Binding: Hardcover

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ASIN: 0824796152

Book Description

"Based on the First International Symposium on Metals and Genetics held recently at the Hospital for Sick Children in Toronto, Ontario, Canada. The only book of its kind to focus on the effects of metals on DNA. Provides up-to-date information on new developments in the field and their wide-ranging implications. Discusses the molecular mechanisms of metal-induced mutagenicity and carcinogenicity."

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Genetic Response to Metals
SARKAR
Manufacturer: NY
ProductGroup: Book
Binding: Hardcover
ASIN: B000MUGSAY

Book Description

Glycostructures play a highly diverse and crucial role in a myriad of organisms and important systems in biology, physiology, medicine, bioengineering and technology. Only in recent years have the tools been developed to partly understand the highly complex functions and the chemistry behind them, but many facts still remain undiscovered. "All roads lead to carbohydrates ... we cannot do without them." (K.C. Nicolaou). Presently the field is experiencing a "quantum jump". Therefore the editors have drawn together in this three volume set plus an accompanying CD-ROM, the complete and up-to-date information on glycostructures, their chemistry and chemical biology, and present them in the form of a comprehensive and strictly systematic survey. The texts are furnished by 2.670 figures, chemical structures and reaction schemes (including more than 12.000 individual chemical reactions), and more than 9.000 references.

Carbohydrates, Volume 14 (Biochemistry of Plants)

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Carbohydrates, Volume 14 (Biochemistry of Plants)

Manufacturer: Academic Press
ProductGroup: Book
Binding: Hardcover

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ASIN: 0126754144

Chitin and Chitinases (Experientia Supplementum)

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Chitin and Chitinases (Experientia Supplementum)

Manufacturer: Birkhäuser Basel
ProductGroup: Book
Binding: Hardcover

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ASIN: 3764358157

Book Description

Chitin is the most abundant nitrogen-bearing organic compound found in nature: it is a common constituent of insect exoskeletons, shells of crustaceans and fungal cell walls. After a short presentation of this polysaccharide in the environment, the first part of this work is devoted to chitin biosynthesis in vitro and in vivo. The second part discusses biochemical, structural and evolutionary aspects concerning chitinases. The third part of the book is devoted to chitosan, an important chitin derivative, which occurs in the composition of threads, fibres, films and gels.

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Techniques in Glycobiology

Manufacturer: CRC
ProductGroup: Book
Binding: Hardcover

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ASIN: 0824798228

Book Description

This work covers methodologies for plant and animal glycoconjugate analysis. It details mass spectrometry, nuclear magnetic resonance spectroscopy, glycolipids and new physical methods, o-glycosylation characterization, chromophore and fluorophore labelling of oligosaccharides, separations, exoglycosidases and mapping, and plant glycobiology.

Synthesis of Naturally Occuring Nitrogen Heterocycles from Carbohydrates

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Synthesis of Naturally Occuring Nitrogen Heterocycles from Carbohydrates
El Ashry , and Ahmed El Nemr
Manufacturer: Blackwell Publishing
ProductGroup: Book
Binding: Hardcover

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ASIN: 1405129344

Book Description

Carbohydrates are widely distributed in nature and widely available, and so are considered as a promising feedstock for the preparation of many organic chemical compounds. They are particularly useful in the preparation of nitrogen heterocycles because of their related structural characteristics and easy availability.Synthesis of Naturally Occurring Nitrogen Heterocycles from Carbohydrates will review the recent literature dealing with use of carbohydrates as raw materials in the synthesis of these materials. The text contains six chapters arranged according to the complexity of the heterocyclic compounds discussed, ranging from five to seven membered rings and from single to multiple fused rings. The book provides a detailed discussion of the various synthetic approaches to these compounds, using carbohydrate starting materials, and does not merely reference synthetic methodology but attempts to give as much detail as possible on the actual experimental conditions used, in such a way that the chemist can use the information directly to design a multi-step synthesis. It discusses the different approaches to the synthesis of a wide range of naturally occurring nitrogen heterocycles in a format that enables the reader to make comparisons and decisions on whether to use a certain procedure, to modify it, or to devise a new synthetic methodology.

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Excellent introduction

Introduction to Glycobiology
Maureen E. Taylor , and Kurt Drickamer
Manufacturer: Oxford University Press, USA
ProductGroup: Book
Binding: Paperback

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ASIN: 0199282781

Book Description

We are all familiar with sugar as a vital source of energy. Yet the biological importance of the sugars extends way beyond their value as a cellular fuel. Introduction to Glycobiology reveals the true impact of the sugars on biological systems, explaining their functions at the molecular, cellular, and organismal level. With a new two-part structure, the book leads us through the essential principles and concepts upon which the discipline is grounded, before exploring the diverse roles of sugars throughout biological systems, including development, cell signalling, and protein trafficking. It also describes the importance of glycobiology in disease, and explains how an understanding of the link between the two is enabling us to develop new therapeutic strategies. Taking the student from the fundamental principles to the frontiers of the subject, and with more learning features to get the most from their studies, Introduction to Glycobiology remains the ideal resource for students and teachers alike. Online Resource Centre For Lecturers: - Full Colour figures to fully engage their students during classes. For Students: - Hyperlinks to the primary literature, and full articles from appropriate OUP journals, to facilitate access to these additional resources - 3D models of key structures, to help students visualize structures, and gain a proper appreciation of the link between structure and function. - Answers to problems, to aid assessment. - Updates - surveys of key developments in the field, provided on a six-monthly basis, to maintain the currency of the resource.

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Excellent introduction.......2007-06-12

This book provides an excellent introduction to the fast growing field of glycobiology. Highly recommended for both student and teacher alike!

Essentials of Carbohydrate Chemistry and Biochemistry

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Essentials of Carbohydrate Chemistry and Biochemistry
Thisbe K. Lindhorst
Manufacturer: John Wiley & Sons
ProductGroup: Book
Binding: Paperback

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ASIN: 3527306641

Book Description

Carbohydrates are the most abundant natural products, in line with their role as energy stores and structural building blocks in plants and algae. They are versatile enough to serve as encoders of biological information and, last but not least, they are involved in a variety of molecular recognition processes. Research into carbohydrate and glycoconjugate functions in cell-to-cell communication processes has even created a new and rapidly developing field of study: glycobiology.

Thisbe Lindhorst's successful book is now available in its second edition. Going from the basic concepts right up to the most recent results, this didactically written book features numerous practical examples of synthetic and analytical methods. The contents have been thoroughly updated, and a new chapter on mass spectroscopy of carbohydrates has been added.
With its clear and lucid style, this introduction to carbohydrate chemistry and biochemistry is essential reading for students and postgraduate scientists in chemistry, biochemistry, pharmacy and biomedicine.

"a very readable book which presents carbohydrate chemistry and, in later sections, biochemistry as exciting areas to work and study. The author captures a sense of wonder and inspiration from the very elegance of these areas of science and their application in the real worlds of pharmaceutical and medical research."
(The Alchemist)

Frontiers in Modern Carbohydrate Chemistry (Acs Symposium Series)

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Frontiers in Modern Carbohydrate Chemistry (Acs Symposium Series)

Manufacturer: An American Chemical Society Publication
ProductGroup: Book
Binding: Hardcover

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ASIN: 0841239703

Book Description

Recent understanding of the involvement of carbohydrate molecules and conjugates in many vital biological processes and, consequently, the appreciation of their tremendous therapeutic potential has stimulated the development of new methods for the synthesis of this class of compounds. The main efforts in the field of synthetic carbohydrate chemistry have been focused on the development of new glycosylation methodologies and convergent strategies for oligosaccharide synthesis, in which the number of synthetic and purification steps is reduced. As a result, many efficient approaches have been developed both on the solid phase and in solution. This book brings together leading specialists working in the emerging areas of chemistry and biology on specific topics in the area of carbohydrates. As a result, the book will be of great interest to scientists solving carbohydrate puzzles in many diverse areas of research.

Saponins (Chemistry and Pharmacology of Natural Products)

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Saponins (Chemistry and Pharmacology of Natural Products)
K. Hostettmann , and A. Marston
Manufacturer: Cambridge University Press
ProductGroup: Book
Binding: Paperback

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ASIN: 0521020174

Book Description

This book is a timely incursion into the field and provides information about occurrence and distribution, structural types, isolation, analysis and structure determination of saponins. Biological and pharmacological activities are discussed, as are aspects of commerical and industrial use. Numerous examples are presented, providing a valuable source of data for the different classes of compound.

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Carbohydrate-based Drug Discovery

Manufacturer: Wiley-VCH
ProductGroup: Book
Binding: Hardcover

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ASIN: 3527306323

Book Description

This handbook presents the latest knowledge on carbohydrate chemistry and biochemistry so as to exploit the full potential of this diverse compound class for the development of novel active substances. While it is unique in covering the entire field, particular emphasis is placed on carbohydrates with pharmaceutical potential. Topics include the following:

Chemical synthesis of carbohydrates
Carbohydrate biosynthesis and metabolism
Carbohydrate analysis
Cellular functions of carbohydrates
Development of carbohydrate-based drugs

A premier resource for carbohydrate chemists and drug developers, this comprehensive two-volume work contains contributions by more than 50 of the world's leading carbohydrate chemists.

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